Quais seriam as outras possíveis conferências de Zinkernagel na Bahia?

Quando foi acertada a conferência do Prof. Rolf Zinkernagel na Bahia, ele apresentou três possibilidades de tema, com pequenas descrições. O tema da conferência proferida apresentado foi “Why do we not have a vaccine against HIV or TB”, que além dos comentários acima também já teve seu resumo divulgado (aqui).

Abaixo estão as duas opções adicionais de conferência que haviam sido oferecidas por ele:

"A Nobel Prize from Unexpected Experimental Results

The role of chance observations leading to key discoveries versus the rational of careful analysis of hypotheses is analysed. Once we know all details from the molecular to the physiological level of all things knowable, we will be able to ask reasonable questions and get answers that can be properly placed. Until then we probably have to rely heavily on observations that yield unexpected results. A few examples will be presented, including so called MHC restricted T cell recognition, the lack of a immune response against many self antigens without T cells or B cells having been eliminated by classical mechanisms, the role of immunopathology in explaining not only chronic or degenerative tolerance types of diseases, but also of so called autoimmune diseases.

Infection & Immunity: Basic Research and Medical Application

Infectious diseases and immune protection against such infections is used here to exploit basic immunological mechanisms and to confront these insights with current immunological dogma. Various concepts, including so called tolerance, i.e. absence of an immune response against self- or foreign antigens, the idea of immunological memory or the concept of immunological specificy are reviewed. These well accepted concepts will be confronted with experimental findings that question the biological and medical relevance of many theoretical concepts and demonstrate alternative possibilities that may be exploited medically."

 

Qual das três você teria escolhido?